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| # | Issuer | Value | Shares | % Portfolio |
|---|---|---|---|---|
| 1 | KYMERA THERAPEUTICS INC | $458.3M | 5502710 | 14.60% |
| 2 | MOONLAKE IMMUNOTHERAPEUTICS | $298.3M | 16001284 | 9.50% |
| 3 | REVOLUTION MEDICINES INC | $277.8M | 2856782 | 8.85% |
| 4 | NEKTAR THERAPEUTICS | $184.2M | 2559595 | 5.87% |
| 5 | STRUCTURE THERAPEUTICS INC | $166.7M | 3459358 | 5.31% |
| 6 | MIRUM PHARMACEUTICALS INC | $146.4M | 1584727 | 4.66% |
| 7 | GH RESEARCH PLC | $121.6M | 8650158 | 3.87% |
| 8 | PALVELLA THERAPEUTICS INC NE | $119.8M | 960989 | 3.82% |
| 9 | ZYMEWORKS INC | $93.5M | 3734142 | 2.98% |
| 10 | XENCOR INC | $86.0M | 7133720 | 2.74% |
| 11 | STOKE THERAPEUTICS INC | $82.9M | 2547557 | 2.64% |
| 12 | CULLINAN THERAPEUTICS INC | $81.7M | 5750683 | 2.60% |
| 13 | DISC MEDICINE INC | $81.4M | 1272312 | 2.59% |
| 14 | XOMA ROYALTY CORPORATION | $81.3M | 2590303 | 2.59% |
| 15 | OLEMA PHARMACEUTICALS INC | $79.0M | 5295893 | 2.52% |
| 16 | TYRA BIOSCIENCES INC | $75.7M | 1976196 | 2.41% |
| 17 | MONTE ROSA THERAPEUTICS INC | $73.4M | 4460886 | 2.34% |
| 18 | ALKERMES PLC | $70.7M | 2000000 | 2.25% |
| 19 | KURA ONCOLOGY INC | $68.7M | 8445769 | 2.19% |
| 20 | AC IMMUNE SA | $54.5M | 19822436 | 1.74% |
| 21 | CRESCENT BIOPHARMA INC. | $50.5M | 2748763 | 1.61% |
| 22 | ANNEXON INC | $48.2M | 8698173 | 1.54% |
| 23 | COMPASS THERAPEUTICS INC | $41.1M | 7764842 | 1.31% |
| 24 | IMMUNOCORE HLDGS PLC | $39.0M | 1294463 | 1.24% |
| 25 | SEPTERNA INC | $32.5M | 1353249 | 1.04% |
| 26 | SUTRO BIOPHARMA INC | $31.2M | 1251788 | 0.99% |
| 27 | FOGHORN THERAPEUTICS INC | $27.9M | 5842000 | 0.89% |
| 28 | 4D MOLECULAR THERAPEUTICS IN | $26.8M | 2879289 | 0.85% |
| 29 | INVIVYD INC | $25.4M | 19525000 | 0.81% |
| 30 | AVALO THERAPEUTICS INC | $24.4M | 1632845 | 0.78% |
| 31 | ELEDON PHARMACEUTICALS INC | $19.4M | 6293282 | 0.62% |
| 32 | ANTERIS TECHNOLOGIES GLOBAL | $16.6M | 3000000 | 0.53% |
| 33 | X4 PHARMACEUTICALS INC | $9.2M | 2233742 | 0.29% |
| 34 | IMMUNIC INC | $8.5M | 7652972 | 0.27% |
| 35 | ONKURE THERAPEUTICS INC | $8.2M | 1978972 | 0.26% |
| 36 | TSCAN THERAPEUTICS INC | $5.6M | 5564290 | 0.18% |
| 37 | IMAGENEBIO INC | $5.5M | 1110002 | 0.18% |
| 38 | TENAX THERAPEUTICS INC | $5.4M | 339549 | 0.17% |
| 39 | MOLECULAR PARTNERS AG | $5.4M | 1353968 | 0.17% |
| 40 | INVENTIVA SA | $3.8M | 686040 | 0.12% |
| 41 | ENGENE HOLDINGS INC | $2.5M | 945402 | 0.08% |
Values in USD (reported in $thousands on 13F). Source: SEC EDGAR.