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| # | Issuer | Value | Shares | % Portfolio |
|---|---|---|---|---|
| 1 | CRISPR THERAPEUTICS AG | $153.21B | 3220627 | 25.57% |
| 2 | WAVE LIFE SCIENCES LTD | $132.28B | 18245691 | 22.08% |
| 3 | BIONTECH SE | $79.09B | 889824 | 13.20% |
| 4 | VIR BIOTECHNOLOGY INC | $76.62B | 8550954 | 12.79% |
| 5 | IDEAYA BIOSCIENCES INC | $44.43B | 1333333 | 7.41% |
| 6 | LYELL IMMUNOPHARMA INC | $30.34B | 1512659 | 5.06% |
| 7 | CYTOKINETICS INC | $22.44B | 340434 | 3.74% |
| 8 | SPERO THERAPEUTICS INC | $21.51B | 9190606 | 3.59% |
| 9 | FULCRUM THERAPEUTICS INC | $13.70B | 1785714 | 2.29% |
| 10 | CVRX INC | $9.53B | 1007583 | 1.59% |
| 11 | BICYCLE THERAPEUTICS PLC | $7.10B | 1529561 | 1.18% |
| 12 | NKARTA INC | $6.65B | 3150732 | 1.11% |
| 13 | REGENXBIO INC | $2.27B | 271456 | 0.38% |
Values in USD (reported in $thousands on 13F). Source: SEC EDGAR.