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| # | Issuer | Value | Shares | % Portfolio |
|---|---|---|---|---|
| 1 | STATE STR SPDR S&P 500 ETF TPUT | $1.37B | 2100000 | 25.10% |
| 2 | ISHARES TRPUT | $868.0M | 3500000 | 15.95% |
| 3 | TRAVERE THERAPEUTICS INC | $145.5M | 4897417 | 2.67% |
| 4 | PTC THERAPEUTICS INC | $141.3M | 2074449 | 2.60% |
| 5 | AGIOS PHARMACEUTICALS INCCALL | $108.3M | 3200000 | 1.99% |
| 6 | SUPERNUS PHARMACEUTICALS | $98.0M | 1895347 | 1.80% |
| 7 | NEUROCRINE BIOSCIENCES INC | $95.4M | 724000 | 1.75% |
| 8 | AGIOS PHARMACEUTICALS INC | $91.9M | 2716000 | 1.69% |
| 9 | IMMUNOVANT INC | $88.6M | 3564916 | 1.63% |
| 10 | FRESHPET INC | $64.5M | 1093307 | 1.18% |
| 11 | INCYTE CORP | $61.8M | 656817 | 1.14% |
| 12 | DYNE THERAPEUTICS INC | $57.6M | 3175110 | 1.06% |
| 13 | CYTOKINETICS INCCALL | $56.0M | 850000 | 1.03% |
| 14 | AMAZON COM INC | $54.6M | 262137 | 1.00% |
| 15 | IRONWOOD PHARMACEUTICALS INC | $52.7M | 15028000 | 0.97% |
| 16 | MADRIGAL PHARMACEUTICALS INC | $52.1M | 99583 | 0.96% |
| 17 | CYTOKINETICS INC | $50.4M | 764538 | 0.93% |
| 18 | HARMONY BIOSCIENCES HLDGS IN | $45.5M | 1624000 | 0.84% |
| 19 | THERMO FISHER SCIENTIFIC INC | $45.0M | 91491 | 0.83% |
| 20 | NEKTAR THERAPEUTICS | $41.6M | 578000 | 0.76% |
| 21 | UNITEDHEALTH GROUP INC | $40.0M | 148000 | 0.74% |
| 22 | UBER TECHNOLOGIES INC | $37.3M | 518760 | 0.69% |
| 23 | IMMUNOCORE HLDGS PLC | $35.8M | 1188000 | 0.66% |
| 24 | DENTSPLY SIRONA INC | $34.8M | 3000000 | 0.64% |
| 25 | RIGEL PHARMACEUTICALS INC | $34.6M | 1280000 | 0.64% |
| 26 | DISC MEDICINE INC | $34.3M | 536000 | 0.63% |
| 27 | ALPHABET INC | $34.1M | 118514 | 0.63% |
| 28 | MINERALYS THERAPEUTICS INC | $31.9M | 1176000 | 0.59% |
| 29 | HUBSPOT INC | $31.4M | 128583 | 0.58% |
| 30 | AXOGEN INC | $31.0M | 936000 | 0.57% |
| 31 | ORTHOFIX MED INC | $31.0M | 2700000 | 0.57% |
| 32 | KURA ONCOLOGY INC | $30.4M | 3736000 | 0.56% |
| 33 | AVANOS MED INC | $28.0M | 2000000 | 0.51% |
| 34 | REGENERON PHARMACEUTICALS | $27.9M | 36126 | 0.51% |
| 35 | ALIGN TECHNOLOGY INC | $27.1M | 157959 | 0.50% |
| 36 | PTC THERAPEUTICS INCCALL | $26.6M | 390000 | 0.49% |
| 37 | MONGODB INC | $26.3M | 107296 | 0.48% |
| 38 | ALIBABA GROUP HLDG LTD | $25.6M | 204000 | 0.47% |
| 39 | MEDLINE INC | $25.1M | 564857 | 0.46% |
| 40 | KALVISTA PHARMACEUTICALS INC | $24.9M | 1236000 | 0.46% |
| 41 | DATADOG INC | $24.6M | 208564 | 0.45% |
| 42 | HUMANA INC | $24.5M | 141279 | 0.45% |
| 43 | SENTINELONE INC | $24.4M | 1897849 | 0.45% |
| 44 | VERASTEM INC | $24.3M | 4592000 | 0.45% |
| 45 | FIVE9 INC | $24.2M | 1592000 | 0.44% |
| 46 | INTUITIVE SURGICAL INC | $24.0M | 52043 | 0.44% |
| 47 | GRIFOLS S A | $24.0M | 2988000 | 0.44% |
| 48 | PENN ENTERTAINMENT INC | $23.7M | 1578000 | 0.44% |
| 49 | SOLID BIOSCIENCES INC | $23.0M | 3200000 | 0.42% |
| 50 | GITLAB INC | $22.3M | 1028664 | 0.41% |
Values in USD (reported in $thousands on 13F). Source: SEC EDGAR.