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| # | Issuer | Value | Shares | % Portfolio |
|---|---|---|---|---|
| 1 | APOGEE THERAPEUTICS INC | $714.9M | 8,493,321 | 26.68% |
| 2 | ERASCA INC | $265.1M | 16,382,812 | 9.89% |
| 3 | ORUKA THERAPEUTICS INC | $203.5M | 4,148,428 | 7.60% |
| 4 | SPYRE THERAPEUTICS INC | $185.9M | 3,685,448 | 6.94% |
| 5 | KALVISTA PHARMACEUTICALS INC | $130.3M | 6,474,485 | 4.86% |
| 6 | DIANTHUS THERAPEUTICS INC | $99.0M | 1,180,000 | 3.70% |
| 7 | DAMORA THERAPEUTICS INC | $93.3M | 3,603,595 | 3.48% |
| 8 | OCULAR THERAPEUTIX INC | $87.6M | 10,346,926 | 3.27% |
| 9 | COGENT BIOSCIENCES INC | $77.0M | 2,000,000 | 2.87% |
| 10 | VIRIDIAN THERAPEUTICS INC | $75.9M | 3,882,709 | 2.83% |
| 11 | SAVARA INC | $75.0M | 13,740,375 | 2.80% |
| 12 | ENLIVEN THERAPEUTICS INC | $67.7M | 1,726,331 | 2.53% |
| 13 | ORIC PHARMACEUTICALS INC | $54.7M | 4,319,765 | 2.04% |
| 14 | VOR BIOPHARMA INC | $54.3M | 3,041,719 | 2.03% |
| 15 | MAZE THERAPEUTICS INC | $47.8M | 1,602,034 | 1.78% |
| 16 | CYTOMX THERAPEUTICS INC | $46.9M | 9,982,124 | 1.75% |
| 17 | JADE BIOSCIENCES INC | $45.2M | 3,220,364 | 1.69% |
| 18 | DYNE THERAPEUTICS INC | $39.4M | 2,173,913 | 1.47% |
| 19 | CRESCENT BIOPHARMA INC. | $39.2M | 2,133,576 | 1.46% |
| 20 | ZURA BIO LTD | $38.3M | 6,434,990 | 1.43% |
| 21 | RELMADA THERAPEUTICS INC | $33.7M | 4,843,380 | 1.26% |
| 22 | ENGENE HOLDINGS INC | $32.5M | 4,771,414 | 1.21% |
| 23 | TENAX THERAPEUTICS INC | $26.8M | 1,675,262 | 1.00% |
| 24 | ADLAI NORTYE LTD | $22.2M | 3,212,731 | 0.83% |
| 25 | CENTURY THERAPEUTICS INC | $19.7M | 8,695,652 | 0.73% |
| 26 | CULLINAN THERAPEUTICS INC | $19.6M | 1,379,965 | 0.73% |
| 27 | CYBIN INC | $18.5M | 3,851,654 | 0.69% |
| 28 | SURROZEN INC | $18.4M | 632,931 | 0.69% |
| 29 | SEPTERNA INC | $12.2M | 506,056 | 0.45% |
| 30 | KORRO BIO INC | $11.4M | 1,009,500 | 0.43% |
| 31 | ALTO NEUROSCIENCE INC | $11.2M | 500,000 | 0.42% |
| 32 | ARTIVA BIOTHERAPEUTICS INC | $10.4M | 1,609,569 | 0.39% |
| 33 | X4 PHARMACEUTICALS INC | $1.4M | 330,525 | 0.05% |
Values in USD (reported in $thousands on 13F). Source: SEC EDGAR.