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| # | Issuer | Value | Shares | % Portfolio |
|---|---|---|---|---|
| 1 | Natera Inc | $310.0M | 1,550,280 | 11.80% |
| 2 | iShares TRPUT | $148.8M | 600,000 | 5.66% |
| 3 | SPDR Series TrustPUT | $134.1M | 1,050,000 | 5.10% |
| 4 | Bristol-Myers Squibb Co | $120.6M | 1,988,721 | 4.59% |
| 5 | Jazz Pharmaceuticals PLC | $113.1M | 598,327 | 4.31% |
| 6 | Vera Therapeutics Inc | $112.4M | 2,793,987 | 4.28% |
| 7 | United Therapeutics Corp | $94.9M | 160,070 | 3.61% |
| 8 | AstraZeneca PLC | $89.9M | 456,031 | 3.42% |
| 9 | Invesco QQQ TRPUT | $86.6M | 150,000 | 3.30% |
| 10 | Cogent Biosciences Inc | $81.4M | 2,113,551 | 3.10% |
| 11 | iShares TRPUT | $80.2M | 475,000 | 3.05% |
| 12 | Ultragenyx Pharmaceutical Inc | $65.9M | 3,145,888 | 2.51% |
| 13 | Rapport Therapeutics Inc | $59.6M | 1,904,408 | 2.27% |
| 14 | Insmed Inc | $56.6M | 346,075 | 2.15% |
| 15 | Alcon AG | $55.0M | 729,972 | 2.09% |
| 16 | Supernus Pharmaceuticals | $49.3M | 954,309 | 1.88% |
| 17 | United Therapeutics CorpPUT | $47.6M | 80,300 | 1.81% |
| 18 | BioMarin Pharmaceutical Inc | $44.2M | 781,982 | 1.68% |
| 19 | Biogen Inc | $42.1M | 229,521 | 1.60% |
| 20 | Celcuity Inc | $41.8M | 366,175 | 1.59% |
| 21 | BioAge Labs Inc | $40.1M | 2,293,788 | 1.53% |
| 22 | Rhythm Pharmaceuticals Inc | $39.1M | 450,096 | 1.49% |
| 23 | Arrivent BioPharma Inc | $39.1M | 1,696,752 | 1.49% |
| 24 | IDEAYA Biosciences Inc | $37.7M | 1,131,786 | 1.44% |
| 25 | Immunome Inc | $37.2M | 1,701,904 | 1.42% |
| 26 | Nektar Therapeutics | $36.7M | 509,546 | 1.40% |
| 27 | Axsome Therapeutics Inc. | $36.0M | 212,747 | 1.37% |
| 28 | Immatics N.V | $35.7M | 3,630,454 | 1.36% |
| 29 | Celcuity IncPUT | $34.2M | 300,000 | 1.30% |
| 30 | Axsome Therapeutics Inc.PUT | $33.8M | 200,000 | 1.29% |
| 31 | BridgeBio Pharma Inc | $30.4M | 409,183 | 1.16% |
| 32 | Dyne Therapeutics Inc | $29.6M | 1,633,897 | 1.13% |
| 33 | Inhibrx Biosciences Inc | $27.3M | 406,029 | 1.04% |
| 34 | Dexcom Inc | $24.7M | 393,576 | 0.94% |
| 35 | Pharvaris N V | $23.1M | 818,328 | 0.88% |
| 36 | Pfizer IncCALL | $22.5M | 800,000 | 0.86% |
| 37 | Praxis Precision Medicines Inc | $20.5M | 63,680 | 0.78% |
| 38 | Genmab A/S | $20.2M | 752,261 | 0.77% |
| 39 | Arcus Biosciences Inc | $19.9M | 923,086 | 0.76% |
| 40 | Liquidia CorporationPUT | $18.9M | 500,000 | 0.72% |
| 41 | Xenon Pharmaceuticals Inc | $17.7M | 305,216 | 0.68% |
| 42 | Stryker Corporation | $14.6M | 44,480 | 0.56% |
| 43 | AnaptysBio Inc | $13.8M | 248,253 | 0.52% |
| 44 | Roivant Sciences Ltd | $13.2M | 477,995 | 0.50% |
| 45 | Edgewise Therapeutics Inc | $12.2M | 386,498 | 0.46% |
| 46 | Compass Therapeutics Inc | $10.9M | 2,056,161 | 0.41% |
| 47 | Exelixis IncPUT | $10.8M | 251,500 | 0.41% |
| 48 | Oric Pharmaceuticals Inc | $8.6M | 679,578 | 0.33% |
| 49 | Tango Therapeutics Inc | $8.3M | 395,081 | 0.31% |
| 50 | Tyra Biosciences Inc | $7.8M | 204,015 | 0.30% |
Values in USD (reported in $thousands on 13F). Source: SEC EDGAR.