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| # | Issuer | Value | Shares | % Portfolio |
|---|---|---|---|---|
| 1 | PRAXIS PRECISION MEDICINES I | $10.57B | 32810 | 8.72% |
| 2 | MINERVA NEUROSCIENCES INC | $9.97B | 1655500 | 8.23% |
| 3 | SOLENO THERAPEUTICS INC | $6.70B | 200000 | 5.53% |
| 4 | SOLENO THERAPEUTICS INCPUT | $6.70B | 200000 | 5.53% |
| 5 | OVID THERAPEUTICS INC | $6.26B | 2818459 | 5.16% |
| 6 | COMPASS PATHWAYS PLC | $5.78B | 1045000 | 4.77% |
| 7 | TARSUS PHARMACEUTICALS INC | $5.67B | 80859 | 4.68% |
| 8 | SOLID BIOSCIENCES INC | $5.52B | 766974 | 4.56% |
| 9 | PROMIS NEUROSCIENCES INC | $5.26B | 414219 | 4.34% |
| 10 | EDGEWISE THERAPEUTICS INC | $5.07B | 161000 | 4.19% |
| 11 | UNIQURE NVCALL | $4.91B | 300000 | 4.05% |
| 12 | EUPRAXIA PHARMACEUTICALS INC | $4.78B | 660375 | 3.95% |
| 13 | CYTOMX THERAPEUTICS INC. | $4.23B | 900000 | 3.49% |
| 14 | INVENTIVA SA | $4.14B | 745300 | 3.41% |
| 15 | PERSPECTIVE THERAPEUTICS INC | $3.86B | 926557 | 3.19% |
| 16 | ABIVAX SA | $3.75B | 33712 | 3.10% |
| 17 | ALUMIS INC | $3.68B | 166959 | 3.04% |
| 18 | UROGEN PHARMA LTD | $3.63B | 202124 | 3.00% |
| 19 | CAPRICOR THERAPEUTICS INC | $3.46B | 113899 | 2.86% |
| 20 | MAZE THERAPEUTICS INCCALL | $2.98B | 100000 | 2.46% |
| 21 | WHITEHAWK THERAPEUTICS INC | $2.82B | 817939 | 2.33% |
| 22 | COMPASS THERAPEUTICS INCCALL | $2.65B | 500000 | 2.18% |
| 23 | INHIBIKASE THERAPEUTICS INC | $2.23B | 1325000 | 1.84% |
| 24 | REPLIMUNE GROUP INCCALL | $1.89B | 246900 | 1.56% |
| 25 | AN2 THERAPEUTICS INC | $1.80B | 526315 | 1.49% |
| 26 | RELMADA THERAPEUTICS INC | $1.47B | 210525 | 1.21% |
| 27 | KARYOPHARM THERAPEUTICS INCCALL | $1.39B | 250000 | 1.15% |
Values in USD (reported in $thousands on 13F). Source: SEC EDGAR.