TCG Crossover Management, LLC

Est. AUM

$3.50B

13F long equity, this entity only

Positions

Period

Mar 2026 (Q1)

SEC EDGAR

View filings ↗

Mar 2026 (Q1)

#	Issuer	Class	Value	Shares	% Portfolio	Discretion
1	ABIVAX SA AMERICAN DEPOSITARY SHARES	ADRS	$721.7M	6481085	20.65%	SOLE
2	CG ONCOLOGY INC	COMM	$248.4M	3670206	7.11%	SOLE
3	TANGO THERAPEUTICS INC	COMM	$220.3M	10531071	6.30%	SOLE
4	COGENT BIOSCIENCES INC	COMM	$190.4M	4946894	5.45%	SOLE
5	CENTESSA PHARMACEUTICALS PLC	ADRS	$170.3M	4286480	4.87%	SOLE
6	DIANTHUS THERAPEUTICS INC	COMM	$140.7M	1676624	4.03%	SOLE
7	TYRA BIOSCIENCES INC	COMM	$124.4M	3248980	3.56%	SOLE
8	IMMUNOVANT INC	COMM	$110.7M	4457988	3.17%	SOLE
9	BIOCRYST PHARMACEUTICALS INC	COMM	$104.9M	11020968	3.00%	SOLE
10	MIRUM PHARMACEUTICALS INC	COMM	$98.1M	1062049	2.81%	SOLE
11	VOR BIOPHARMA INC	COMM	$96.5M	5673078	2.76%	SOLE
12	SPYRE THERAPEUTICS INC	COMM	$95.9M	1900582	2.74%	SOLE
13	AMYLYX PHARMACEUTICALS INC	COMM	$86.8M	6243812	2.48%	SOLE
14	DISC MEDICINE INC	COMM	$85.8M	1341862	2.45%	SOLE
15	DYNE THERAPEUTICS INC	COMM	$83.7M	4615144	2.39%	SOLE
16	MONTE ROSA THERAPEUTICS INC	COMM	$76.0M	4622151	2.18%	SOLE
17	SAVARA INC	COMM	$67.5M	12362205	1.93%	SOLE
18	REVOLUTION MEDICINES INC	COMM	$56.1M	576473	1.60%	SOLE
19	KODIAK SCIENCES INC	COMM	$55.1M	1445538	1.58%	SOLE
20	LB PHARMACEUTICALS INC	COMM	$45.3M	1839489	1.30%	SOLE
21	SURROZEN INC	COMM	$42.9M	1473101	1.23%	SOLE
22	ADC THERAPEUTICS SA	COMM	$42.7M	11390175	1.22%	SOLE
23	RELAY THERAPEUTICS INC	COMM	$42.5M	4273356	1.22%	SOLE
24	FULCRUM THERAPEUTICS INC	COMM	$40.3M	5250000	1.15%	SOLE
25	BIOHAVEN LTD	COMM	$39.2M	4631317	1.12%	SOLE
26	CENTURY THERAPEUTICS INC	COMM	$39.0M	17754430	1.12%	SOLE
27	TECTONIC THERAPEUTIC INC	COMM	$37.2M	1204891	1.07%	SOLE
28	PERSPECTIVE THERAPEUTICS INC	COMM	$33.0M	7915567	0.94%	SOLE
29	XENCOR INC	COMM	$29.6M	2452138	0.85%	SOLE
30	ENTRADA THERAPEUTICS INC	COMM	$28.9M	2287500	0.83%	SOLE
31	ALX ONCOLOGY HOLDINGS INC	COMM	$26.1M	13011849	0.75%	SOLE
32	ARVINAS HOLDING CO LLC	COMM	$25.3M	2387461	0.72%	SOLE
33	JANUX THERAPEUTICS INC	COMM	$24.9M	1789617	0.71%	SOLE
34	AGOMAB THERAPEUTICS NV	ADRS	$21.5M	2053233	0.62%	SOLE
35	ALECTOR INC	COMM	$21.5M	10000000	0.62%	SOLE
36	MBX BIOSCIENCES INC	COMM	$19.4M	650000	0.56%	SOLE
37	SILENCE THERAPEUTICS PLC	ADRS	$16.0M	3033560	0.46%	SOLE
38	LIQUIDIA TECHNOLOGIES INC	COMM	$15.2M	403048	0.44%	SOLE
39	OCULAR THERAPEUTIX INC	COMM	$14.0M	1647752	0.40%	SOLE
40	AVALO THERAPEUTICS INC	COMM	$11.0M	738383	0.32%	SOLE
41	UROGEN PHARMA LTD	COMM	$7.3M	405365	0.21%	SOLE
42	MONOPAR THERAPEUTICS INC	COMM	$7.2M	132103	0.21%	SOLE
43	CONTEXT THERAPEUTICS INC	COMM	$7.0M	2682696	0.20%	SOLE
44	STRUCTURE THERAPEUTICS INC	ADRS	$6.8M	140411	0.19%	SOLE
45	CULLINAN THERAPEUTICS INC	COMM	$5.8M	406786	0.17%	SOLE
46	KORRO BIO INC	COMM	$4.7M	416301	0.13%	SOLE
47	LEONABIO INC	COMM	$4.7M	464398	0.13%	SOLE
48	UPSTREAM BIO INC	COMM	$1.6M	181063	0.05%	SOLE
49	VISTAGEN THERAPEUTICS INC	COMM	$1.5M	2676580	0.04%	SOLE

Values in USD (reported in $thousands on 13F). Source: SEC EDGAR.