Frazier Life Sciences Management, L.P.

Est. AUM

$3.89B

13F long equity, this entity only

Positions

Period

Mar 2026 (Q1)

SEC EDGAR

View filings ↗

Mar 2026 (Q1)

#	Issuer	Class	Value	Shares	% Portfolio	Discretion
1	MIRUM PHARMACEUTICALS INC	COM	$709.4M	7679684	18.25%	SOLE
2	NEWAMSTERDAM PHARMA COMPANY	ORDINARY SHARES	$542.4M	16943774	13.96%	SOLE
3	ERASCA INC	COM	$399.2M	24675188	10.27%	SOLE
4	BRIDGEBIO PHARMA INC	COM	$256.1M	3448139	6.59%	SOLE
5	ARCUTIS BIOTHERAPEUTICS INC	COM	$232.6M	9874511	5.99%	SOLE
6	MBX BIOSCIENCES INC	COM	$198.6M	6652013	5.11%	SOLE
7	PHATHOM PHARMACEUTICALS INC	COM	$138.5M	12466489	3.56%	SOLE
8	MAZE THERAPEUTICS INC	COM	$136.3M	4567274	3.51%	SOLE
9	KRYSTAL BIOTECH INC	COM	$124.3M	481307	3.20%	SOLE
10	TREVI THERAPEUTICS INC	COM	$118.6M	9939547	3.05%	SOLE
11	PALVELLA THERAPEUTICS INC NE	COM	$110.0M	882400	2.83%	SOLE
12	KALVISTA PHARMACEUTICALS INC	COM	$99.9M	4961108	2.57%	SOLE
13	DISC MEDICINE INC	COM	$86.6M	1354852	2.23%	SOLE
14	CYTOKINETICS INC	COM NEW	$76.4M	1159879	1.97%	SOLE
15	REVOLUTION MEDICINES INC	COM	$65.7M	675686	1.69%	SOLE
16	DYNE THERAPEUTICS INC	COM	$57.2M	3153082	1.47%	SOLE
17	SAVARA INC	COM	$53.1M	9720852	1.37%	SOLE
18	TARSUS PHARMACEUTICALS INC	COM	$51.1M	728644	1.32%	SOLE
19	VOR BIOPHARMA INC	COM NEW	$45.4M	2543939	1.17%	SOLE
20	AGIOS PHARMACEUTICALS INC	COM	$42.5M	1256080	1.09%	SOLE
21	BIOCRYST PHARMACEUTICALS INC	COM	$38.2M	4009240	0.98%	SOLE
22	ZAI LAB LTD	ADR	$35.8M	1902320	0.92%	SOLE
23	AURA BIOSCIENCES INC	COM	$34.1M	5100000	0.88%	SOLE
24	ACADIA PHARMACEUTICALS INC	COM	$32.0M	1438198	0.82%	SOLE
25	ASCENDIS PHARMA A/S	SPONSORED ADR	$30.5M	133333	0.78%	SOLE
26	LEXEO THERAPEUTICS INC	COM	$25.4M	4424725	0.65%	SOLE
27	ALKERMES PLC	SHS	$24.8M	700647	0.64%	SOLE
28	ACLARIS THERAPEUTICS INC	COM	$18.5M	4925374	0.48%	SOLE
29	MONTE ROSA THERAPEUTICS INC	COM	$16.4M	1000000	0.42%	SOLE
30	IMMUNOCORE HLDGS PLC	ADS	$14.6M	484782	0.38%	SOLE
31	MANNKIND CORP	COM NEW	$14.5M	5900000	0.37%	SOLE
32	VALNEVA SE	SPONSORED ADS	$14.3M	2291666	0.37%	SOLE
33	EVOLUS INC	COM	$10.8M	2630665	0.28%	SOLE
34	NEWAMSTERDAM PHARMA COMPANY	*W EXP 99/99/999	$10.0M	500333	0.26%	SOLE
35	ALLOGENE THERAPEUTICS INC	COM	$9.3M	3796668	0.24%	SOLE
36	AUTOLUS THERAPEUTICS LTD	SPON ADS	$6.1M	4447910	0.16%	SOLE
37	IBIO INC	COM NEW	$3.7M	1953467	0.10%	SOLE
38	XILIO THERAPEUTICS INC	COM	$3.6M	422505	0.09%	SOLE

Values in USD (reported in $thousands on 13F). Source: SEC EDGAR.