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| # | Issuer | Value | Shares | % Portfolio |
|---|---|---|---|---|
| 1 | TANGO THERAPEUTICS INC | $227.5M | 10876219 | 29.87% |
| 2 | KODIAK SCIENCES INC | $51.9M | 1361000 | 6.81% |
| 3 | REVOLUTION MEDICINES INC | $48.6M | 500000 | 6.38% |
| 4 | KYMERA THERAPEUTICS INC | $27.4M | 329100 | 3.60% |
| 5 | CELCUITY INC | $25.7M | 225000 | 3.37% |
| 6 | SURROZEN INC | $22.3M | 766318 | 2.93% |
| 7 | ABIVAX SA | $22.3M | 200000 | 2.92% |
| 8 | TERNS PHARMACEUTICALS INC | $19.8M | 375000 | 2.60% |
| 9 | VAXCYTE INC | $18.9M | 325000 | 2.48% |
| 10 | CAPRICOR THERAPEUTICS INC | $17.9M | 590000 | 2.35% |
| 11 | PROTAGONIST THERAPEUTICS INC | $17.9M | 170000 | 2.35% |
| 12 | VIR BIOTECHNOLOGY INC | $16.7M | 1866000 | 2.20% |
| 13 | CORVUS PHARMACEUTICALS INC | $16.1M | 1100000 | 2.11% |
| 14 | PRAXIS PRECISION MEDICINES I | $15.0M | 46457 | 1.97% |
| 15 | PTC THERAPEUTICS INC | $13.6M | 200000 | 1.79% |
| 16 | PRECIGEN INC | $13.5M | 3500000 | 1.78% |
| 17 | DEFINIUM THERAPEUTICS INC | $11.3M | 598500 | 1.49% |
| 18 | AMYLYX PHARMACEUTICALS INC | $11.1M | 800000 | 1.46% |
| 19 | UNIQURE NV | $10.8M | 662000 | 1.42% |
| 20 | OPUS GENETICS INC | $10.2M | 2250000 | 1.34% |
| 21 | CORCEPT THERAPEUTICS INC | $10.1M | 250000 | 1.32% |
| 22 | UROGEN PHARMA LTD | $9.0M | 500000 | 1.18% |
| 23 | REPLIMUNE GROUP INC | $9.0M | 1175000 | 1.18% |
| 24 | COGENT BIOSCIENCES INC | $8.7M | 225000 | 1.14% |
| 25 | PALISADE BIO INC | $8.4M | 4799875 | 1.10% |
| 26 | CRESCENT BIOPHARMA INC. | $8.3M | 453686 | 1.09% |
| 27 | SOLENO THERAPEUTICS INC | $6.7M | 200000 | 0.88% |
| 28 | ALLOGENE THERAPEUTICS INC | $6.6M | 2725000 | 0.87% |
| 29 | CYTOKINETICS INC | $6.6M | 100000 | 0.87% |
| 30 | CONTINEUM THERAPEUTICS INC | $6.5M | 494000 | 0.85% |
| 31 | APOGEE THERAPEUTICS INC | $5.9M | 70000 | 0.77% |
| 32 | RELMADA THERAPEUTICS INC | $5.9M | 842106 | 0.77% |
| 33 | ZURA BIO LTD | $5.4M | 900000 | 0.70% |
| 34 | MOONLAKE IMMUNOTHERAPEUTICS | $5.1M | 275000 | 0.67% |
| 35 | AVALO THERAPEUTICS INC | $4.5M | 300000 | 0.59% |
| 36 | INOVIO PHARMACEUTICALS INC | $4.1M | 2370122 | 0.54% |
| 37 | STRUCTURE THERAPEUTICS INC | $3.6M | 75000 | 0.47% |
| 38 | SAREPTA THERAPEUTICS INC | $3.3M | 150000 | 0.43% |
| 39 | CYBIN INC | $3.1M | 640000 | 0.40% |
| 40 | OCULAR THERAPEUTIX INC | $3.0M | 350000 | 0.39% |
| 41 | AN2 THERAPEUTICS INC | $2.6M | 749035 | 0.34% |
| 42 | CLENE INC | $2.4M | 477515 | 0.31% |
| 43 | ORIC PHARMACEUTICALS INC | $2.2M | 176500 | 0.29% |
| 44 | SOLID BIOSCIENCES INC | $2.2M | 300000 | 0.28% |
| 45 | INVIVYD INC | $1.9M | 1500000 | 0.26% |
| 46 | LB PHARMACEUTICALS INC | $1.7M | 70000 | 0.23% |
| 47 | KARYOPHARM THERAPEUTICS INC | $1.7M | 302536 | 0.22% |
| 48 | NURIX THERAPEUTICS INC | $1.6M | 100000 | 0.20% |
| 49 | UPSTREAM BIO INC | $1.4M | 150000 | 0.18% |
| 50 | MILESTONE PHARMACEUTICALS IN | $793K | 666666 | 0.10% |
Values in USD (reported in $thousands on 13F). Source: SEC EDGAR.