The State Street SPDR S&P Pharmaceuticals ETF (the "Fund") seeks to provide investment results that, before fees and expenses, correspond generally to the total return performance of an index derived from the pharmaceuticals segment of a U.S.
| # | Holding | Ticker | Weight |
|---|---|---|---|
| 1 | State Street Navigator Securities Lending Portfolio II | — | 8.5788% |
| 2 | Definium Therapeutics Inc | — | 3.0887% |
| 3 | MBX Biosciences Inc | — | 2.7181% |
| 4 | Alumis Inc |
Last synced Oct 27, 2026, 6:25 AM · Price and AUM from Yahoo Finance · Holdings from SEC N-PORT filings
| 2.1407% |
| 5 | AtaiBeckley Inc | — | 2.1275% |
| 6 | Trevi Therapeutics Inc | — | 2.1238% |
| 7 | Enliven Therapeutics Inc | — | 2.0931% |
| 8 | Amylyx Pharmaceuticals Inc | — | 2.0362% |
| 9 | VeraDermics Inc | — | 2.0176% |
| 10 | Ligand Pharmaceuticals Inc | — | 1.9429% |
| 11 | Nuvation Bio Inc | — | 1.8925% |
| 12 | Edgewise Therapeutics Inc | — | 1.8833% |
| 13 | Nektar Therapeutics | — | 1.8762% |
| 14 | Liquidia Corp | — | 1.8646% |
| 15 | Maze Therapeutics Inc | — | 1.8515% |
| 16 | Harrow Inc | — | 1.8052% |
| 17 | EyePoint Inc | — | 1.7698% |
| 18 | Amneal Pharmaceuticals Inc | — | 1.7242% |
| 19 | Ocular Therapeutix Inc | — | 1.7146% |
| 20 | Corcept Therapeutics Inc | — | 1.6984% |
| 21 | Crinetics Pharmaceuticals Inc | — | 1.6638% |
| 22 | Pacira BioSciences Inc | — | 1.6530% |
| 23 | Merck & Co Inc | — | 1.6466% |
| 24 | Indivior Pharmaceuticals Inc | — | 1.6437% |
| 25 | Elanco Animal Health Inc | — | 1.6421% |
| 26 | Johnson & Johnson | — | 1.6253% |
| 27 | Eli Lilly & Co | — | 1.6117% |
| 28 | Jazz Pharmaceuticals PLC | — | 1.6015% |
| 29 | Collegium Pharmaceutical Inc | — | 1.5874% |
| 30 | Bristol-Myers Squibb Co | — | 1.5814% |
| 31 | Supernus Pharmaceuticals Inc | — | 1.5741% |
| 32 | Royalty Pharma PLC | — | 1.5694% |
| 33 | Tarsus Pharmaceuticals Inc | — | 1.5676% |
| 34 | WaVe Life Sciences Ltd | — | 1.5664% |
| 35 | Harmony Biosciences Holdings Inc | — | 1.5660% |
| 36 | Organon & Co | — | 1.5442% |
| 37 | ANI Pharmaceuticals Inc | — | 1.5434% |
| 38 | Viatris Inc | — | 1.5366% |
| 39 | Esperion Therapeutics Inc | — | 1.5357% |
| 40 | Axsome Therapeutics Inc | — | 1.5163% |
| 41 | Innoviva Inc | — | 1.5068% |
| 42 | BioAge Labs Inc | — | 1.4997% |
| 43 | Prestige Consumer Healthcare Inc | — | 1.4682% |
| 44 | Rapport Therapeutics Inc | — | 1.4381% |
| 45 | Pfizer Inc | — | 1.4354% |
| 46 | Omeros Corp | — | 1.4228% |
| 47 | Perrigo Co PLC | — | 1.4194% |
| 48 | Xeris Biopharma Holdings Inc | — | 1.3926% |
| 49 | Zoetis Inc | — | 1.3490% |
| 50 | Eton Pharmaceuticals Inc | — | 1.3049% |