

| # | Holding | Ticker | Weight |
|---|---|---|---|
| 1 | State Street Navigator Securities Lending Portfolio II | — | 5.8747% |
| 2 | Apogee Therapeutics Inc | — | 1.4883% |
| 3 | Moderna Inc | — | 1.4123% |
| 4 | Twist Bioscience Corp | — | 1.4080% |
| 5 | Oruka Therapeutics Inc |
Last synced Oct 27, 2026, 6:25 AM · Price and AUM from Yahoo Finance · Holdings from SEC N-PORT filings
| 1.3786% |
| 6 | Kymera Therapeutics Inc | — | 1.3596% |
| 7 | Viking Therapeutics Inc | — | 1.3039% |
| 8 | Praxis Precision Medicines Inc | — | 1.2903% |
| 9 | Erasca Inc | — | 1.2709% |
| 10 | Revolution Medicines Inc | — | 1.2046% |
| 11 | Rhythm Pharmaceuticals Inc | — | 1.2015% |
| 12 | CG oncology Inc | — | 1.1999% |
| 13 | SELLAS Life Sciences Group Inc | — | 1.1900% |
| 14 | Vaxcyte Inc | — | 1.1870% |
| 15 | Dianthus Therapeutics Inc | — | 1.1831% |
| 16 | Cytokinetics Inc | — | 1.1780% |
| 17 | Natera Inc | — | 1.1630% |
| 18 | Scholar Rock Holding Corp | — | 1.1570% |
| 19 | Roivant Sciences Ltd | — | 1.1554% |
| 20 | Mirum Pharmaceuticals Inc | — | 1.1551% |
| 21 | Cogent Biosciences Inc | — | 1.1439% |
| 22 | Ultragenyx Pharmaceutical Inc | — | 1.1405% |
| 23 | Travere Therapeutics Inc | — | 1.1273% |
| 24 | Alkermes PLC | — | 1.1085% |
| 25 | Krystal Biotech Inc | — | 1.1036% |
| 26 | Celcuity Inc | — | 1.0997% |
| 27 | Relay Therapeutics Inc | — | 1.0989% |
| 28 | Spyre Therapeutics Inc | — | 1.0967% |
| 29 | TG Therapeutics Inc | — | 1.0930% |
| 30 | Beam Therapeutics Inc | — | 1.0794% |
| 31 | Insmed Inc | — | 1.0764% |
| 32 | Protagonist Therapeutics Inc | — | 1.0749% |
| 33 | Arrowhead Pharmaceuticals Inc | — | 1.0688% |
| 34 | Vera Therapeutics Inc | — | 1.0593% |
| 35 | Vertex Pharmaceuticals Inc | — | 1.0572% |
| 36 | Madrigal Pharmaceuticals Inc | — | 1.0567% |
| 37 | AbbVie Inc | — | 1.0375% |
| 38 | Biogen Inc | — | 1.0316% |
| 39 | PTC Therapeutics Inc | — | 1.0315% |
| 40 | Halozyme Therapeutics Inc | — | 1.0298% |
| 41 | uniQure NV | — | 1.0282% |
| 42 | Bridgebio Pharma Inc | — | 1.0249% |
| 43 | CRISPR Therapeutics AG | — | 1.0232% |
| 44 | ImmunityBio Inc | — | 1.0191% |
| 45 | Summit Therapeutics Inc | — | 1.0116% |
| 46 | Ionis Pharmaceuticals Inc | — | 1.0031% |
| 47 | Incyte Corp | — | 0.9978% |
| 48 | Amgen Inc | — | 0.9947% |
| 49 | Neurocrine Biosciences Inc | — | 0.9718% |
| 50 | Gilead Sciences Inc | — | 0.9646% |